Job Description

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Nonclinical Safety

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House Pennsylvania United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Principal Scientist Toxicology in Spring House PA.

Purpose: This Principal Scientist in Nonclinical Safety and Submissions a department in the Preclinical Sciences and Translational Safety (PSTS) organization within Janssen Research & Development supports nonclinical safety evaluation in late discovery and development for various therapeutic areas.

You will be responsible for:

• Design of in vivo general toxicology studies for biologics small molecules and other modalities.
• Integrated scientific data interpretation and critical report review for general toxicology and safety pharmacology studies.
• Oversee and monitor contracted in vivo toxicology and in vitro/in vivo safety pharmacology studies in compliance with Good Laboratory Practices (GLPs) and animal welfare regulations following company policies and standard operating procedures.
• Engagement in multi-disciplinary teams within PSTS and close collaboration with nonclinical project representatives to provide scientific and technical expertise on drug development programs.
• Participate in issue-resolution teams through active engagement in scientific discussions and the shaping of strategies designed to support and inform critical development decisions.
• Provide strong scientific input regarding potential mechanisms of toxicity in molecular pathways and propose appropriate follow-up. Maintain up-to-date knowledge regarding innovative approaches in toxicological research.
• Work independently foster constructive cross-functional collaborations with both internal and external partners and be able to prioritize workload in alignment with pipeline priorities.
• Adhere to timelines; proactively identify and communicate study-related issues and develop contingency plans.
• The candidate will contribute to the success and growth of PSTS through active participation in internal and external committees / working groups and will closely interact with scientists in other functional areas including pathology bioanalysis toxicokinetics and development project leaders in the US Belgium and China.

Qualifications / Requirements:

Education:

• Minimum of Masters Degree in biomedical sciences toxicology pharmacology or similar education is required; Advanced degree is preferred.

Experience/Skills:

• A minimum of 5 years of relevant experience is required.
• Experience as a Study Director or Study Monitor conducting/overseeing in vivo toxicology studies supporting projects in discovery through development is required
• Knowledge of major species typically evaluated as toxicology models is required
• Knowledge in immunology or immunotoxicology is preferred.
• Strong written and verbal communication skills and the ability to negotiate and influence decision-making processes think and manage issues to resolution and contribute to study teams and scientific discussions are required with prior experience in scientific data evaluation integrated safety assessment and scientific writing
• Capable of making fast decisions when necessary while maintaining positive and inclusive team relationships is required
• Personal leadership skills a pro-active and flexible attitude sense of urgency and excellent collaboration skills are required
• Strong critical thinking skills and a strong scientific knowledge in toxicology safety pharmacology pathology and drug metabolism/pharmacokinetics and an ability to apply this knowledge to influence development programs are preferred

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

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Required Skills:

Preferred Skills:

Clinical Data Management Critical Thinking Drug Discovery Development EHS Compliance Emergency Planning Organizing Performance Measurement Presentation Design Process Hazard Analysis (PHA) Process Optimization Program Management Regulatory Affairs Management Risk Management Safety Audits Safety Investigations Safety-Oriented Scientific Research

Required Experience:

Staff IC

Job Tags

Full time, Local area, Flexible hours,

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